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Anatly

Spleen: anatomy, structure and function

Quick answer

The spleen is the largest lymphoid organ, in the left upper abdomen behind the stomach and beneath the ribs. It filters blood, removes old red blood cells and takes part in immune responses. The splenic artery, a branch of the celiac trunk, supplies it.

Key facts

LocationLeft hypochondrium, against the diaphragm, under ribs 9 to 11.
StructureRed pulp for filtering blood, white pulp with lymphoid tissue, hilum for vessels, surrounded by a capsule.
FunctionFilters blood, recycles iron from red blood cells, stores platelets and contributes to immune surveillance.
Blood supplySplenic artery from the celiac trunk; drained by the splenic vein into the portal system.
InnervationCeliac plexus.
3D model of the spleen shown with nearby bones

3D model: BodyParts3D (CC BY 4.0), adult male reference anatomy. Highlighted structure shown with nearby bones for context.

About the spleen

The spleen is not essential for life, but people without a spleen are more susceptible to infections by encapsulated bacteria and receive vaccination advice.

Clinical relevance

Frequently asked questions

Where is the spleen located?

In the left upper quadrant of the abdomen, behind the stomach and protected by the lower ribs.

Can you live without a spleen?

Yes, but the risk of certain serious infections is higher.

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